| 裸鼠同系肿瘤细胞DNA对SF_8传代细胞的体外转染 |
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| 引用本文： | 陈有海,李辉,高天祥,周利华,张卫国. 裸鼠同系肿瘤细胞DNA对SF_8传代细胞的体外转染[J]. 山东大学学报(医学版), 1989, 0(3) |
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| 作者姓名： | 陈有海 李辉 高天祥 周利华 张卫国 |
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| 作者单位： | 山东医科大学免疫学研究室(陈有海，李辉)，首都医学院电镜室(高天祥)，山东医科大学电子显微镜中心实验室(周利华)，山东医科大学电子显微镜中心实验室(张卫国) |
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| 摘 要： | SF_8是一弱转化成纤维细胞系,来源于同系移植的BALB/c裸鼠淋巴肉瘤的间质。本实验证明,SF_8传代细胞可被同系淋巴肉瘤细胞的DNA转染,发生进一步地恶性转化,变为强转化的成纤维细胞(SFtr)。
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| 关 键 词： | SF_8传代细胞 体外转染 裸鼠 |
IN VITRO TRANSFECTION OF SF8 CELL LINE BY ISOGENEIC TUMOR CELL DNA |
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| Chen Youhai,et al Dept.of Microbiology,Shandong Medical University. IN VITRO TRANSFECTION OF SF8 CELL LINE BY ISOGENEIC TUMOR CELL DNA[J]. Journal of Shandong University:Health Sciences, 1989, 0(3) |
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| Authors: | Chen Youhai et al Dept.of Microbiology Shandong Medical University |
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| Abstract: | From our previous studies,we found that the isogeneictransplanted lymphoma cells could induce partial transformation of stro-mal fibroblasts of BALB/c nude mice,known as Horizontal Transforma-tion.In this report,we further demonstrate that the partiallytransformed cell line(SF_8)can be transfected by isogeneic lymphoma cellDNA in vitro,resulted in fully transformed cells.The possibility ofmultistep nature of Horizontal Transformation is discussed. |
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| Keywords: | SF_8 cell In vitro transfection Mice nude |
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