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肝癌切除术后门静脉与肝动脉区域化疗对机体的不同影响
引用本文:陈德,李悦,蒋小峰,林景泰,胡以则. 肝癌切除术后门静脉与肝动脉区域化疗对机体的不同影响[J]. 中国基层医药, 2004, 11(8): 897-898
作者姓名:陈德  李悦  蒋小峰  林景泰  胡以则
作者单位:510260,广州医学院第二附属医院肝胆外科
基金项目:1999年广东省医学科学技术研究基金项目(编号 :A19992 5 4)
摘    要:目的比较肝癌切除术后门静脉与肝动脉区域化疗对机体的不同影响。方法对42例原发性肝癌切除术后行肝动脉或门静脉化疗患者资料进行回顾性分析。结果术后门静脉化疗组的骨髓抑制程度、肝功能损害、胃肠道不良反应均显著低于肝动脉化疗组,对细胞免疫的影响小于肝动脉化疗组。结论经门静脉给药肝脏区域化疗是一种有效且副作用较小的肝癌综合治疗措施。

关 键 词:肝癌 切除术 术后化疗 门静脉注药 肝动脉注药
修稿时间:2003-12-10

The different effects of hepatic artery chemotherapy and portal vein chemotherapy on patients with liver cancer after surgery
CHEN De,LI Yue,JIANG Xiaofeng,et al.. The different effects of hepatic artery chemotherapy and portal vein chemotherapy on patients with liver cancer after surgery[J]. Chinese Journal of Primary Medicine and Pharmacy, 2004, 11(8): 897-898
Authors:CHEN De  LI Yue  JIANG Xiaofeng  et al.
Affiliation:CHEN De,LI Yue,JIANG Xiaofeng,et al.Department of Hepatobiliary Surgery,The Second Affiliated Hospital,Guangzhou Medical College,Guangdong,510260,China
Abstract:Objective To explore the different side effects of hepatic artery chemotherapy and portal vein chemotherapy on patients with liver cancer after surgery.Methods 42 cases were analyzed retrospectively,who underwent local hepatic artery chemotherapy or portal vein chemotherapy for primary hepatocellular carcinoma.Results The bone marrow depression and functional lesion of liver of portal vein chemotherapy were less than those of hepatic artery chemotherapy,and the portal vein chemotherapy had less immuno-suppresion than hepatic artery chemotherapy.Conclusion Portal vein chemotherapy has fewer side effects than that from hepatic artery on patients with primary hepatocellular carcinoma.
Keywords:Primary hepatocellular carcinoma  Port vein  Hepatic artery  Chemotherapy
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