心绞痛患者血清C-反应蛋白测定的临床意义

目的探讨心绞痛患者血清C-反应蛋白(CRP)测定在CHD诊断,治疗中的临床意义。方法观察了83例心绞痛患者入院后1、3、7、152、5日血清CRP浓度的变化,其中稳定性心绞痛(SA)患者38例,不稳定性心绞痛(UA)患者45例。结果UA组血清CRP浓度明显增高,与SA组和对照组间比较有显著差异(P<0.001),SA组与对照组比较,虽然两组同在正常人波动范围内,但有差异(P<0.05)。SA组和UA组患者入院1~25天经治疗后,SA组血清CRP浓度下降不明显。UA组在入院1~3天内CRP下降不明显,以后下降至接近SA组的水平。结论心肌缺血本身并不能明显引起血清CRP浓度的增高。心绞痛从SA到UA的发展过程中,血清CRP浓度在逐渐增高,并随着有效的治疗而接近对照组。因此,血清CRP测定在心绞痛的诊断、治疗中具有一定的临床意义。

Clinical significance of the detection of serum C-reactive protein in angina patients

ObjectiveTo investigation the clinical significance of serum C-reactive protein detection in the diagnosis and treatment of angina patients. MethodsThe vary of serum CRP were observed in 13715 and 25 days after hospitalization in 83 angina patients, consists of 38 cases of stable angina(SA) and 45 cases of unstable angina(UA). ResultsSerum CRP in UA group increased greatly, compared with SA group and the control group(P<0.001). CRP in UA group increased greatly, compared with SA group and the control group(P<0.05). After 125 days hospitalization, CRP descend little in SA group. In UA group, after three days changed, CRP dropped to the same level of SA group. ConclusionThe determination of serum C-reactive protein may be good to the diagnosis and treatment in angina patients.