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2010年海南省1568例药品不良反应/事件报告分析
引用本文:苗会青,林昌文. 2010年海南省1568例药品不良反应/事件报告分析[J]. 中国药物警戒, 2011, 8(9): 562-565
作者姓名:苗会青  林昌文
作者单位:海南省药品不良反应监测中心,海南海口,570216
摘    要:目的探讨海南省2010年药品不良反应/事件的发生特点和规律,为促进临床合理用药提供参考。方法采用Excel电子表格筛选,按患者性别、年龄、药品类别、不良反应临床表现类型、给药途径等进行统计分析。结果≤10岁的儿童不良反应发生率高,药品不良反应涉及的药品以抗微生物药最多,给药途径以静脉用药为主,不良反应累及的系统-器官以皮肤及其附件的损害居多。结论加强药品不良反应监测工作,改变不良用药习惯,减少抗微生物药的应用和静脉给药比例,保障公众用药安全。

关 键 词:药品不良反应  分析

Analysis of 1568 Cases of Adverse Drug Reaction/Event in Hainan Province in 2010
MIAO Hui-qing,LIN Chang-wen. Analysis of 1568 Cases of Adverse Drug Reaction/Event in Hainan Province in 2010[J]. Chinese JOurnal of Pharmacovigilance, 2011, 8(9): 562-565
Authors:MIAO Hui-qing  LIN Chang-wen
Affiliation:MIAO Hui-qing LIN Chang-wen(Center for Adverse Drug Reaction Monitoring of Hainan Province,Hainan Haikou 570216,China)
Abstract:Objective To search the factors,characteristics and rules that lead to adverse drug reaction/event(ADR/ADE) and provide references of the rational use of drugs by analyzing 1568 Cases of ADR/ADE in Hainan Province in 2010.Methods 1568 Cases of ADR/ADE were comprehensively analyzed in respect of the patients' sex,age,drug categories,clinical manifestations and route of administration,etc.by means of Excel.Results Most patients who had ADR/ADE were children(≤10years).Most cases of ADR/ADE were caused by anti-infective drugs.The intravenous medication was the main route of administration result in ADR/ADE.Lesions of the skin and its appendages were the main manifestations of ADR/ADE.Conclution It is to improve rational use of drugs in clinic that ADR monitoring and propaganda should be strengthened,harmful habit of drug use should change,and anti-infective drugs and intravenous medication should be used rationally.
Keywords:adverse drug reaction/event(ADR/ADE)  analysis  
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