| 月经失调运动员下丘脑─垂体─卵巢的内分泌变化 |
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| 引用本文： | 崔丽萍,佟启良,张崇理.月经失调运动员下丘脑─垂体─卵巢的内分泌变化[J].中国运动医学杂志,1996(1). |
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| 作者姓名： | 崔丽萍 佟启良 张崇理 |
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| 作者单位： | 北京体育大学，中国科学院动物研究所 |
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| 摘 要： | 为了探讨运动性闭经及月经失调的发病机制，选择了５３名女运动员作为研究对象。采用放免法（ＲＩＡ）测定闭经组、长月经周期组和对照组血浆基础β—内啡肽（β－ＥＰ）、促性腺激素释放激素（ＧｎＲＨ）、黄体生成素（ＬＨ）、卵泡刺激素（ＦＳＨ）的浓度。结果表明闭经组和长周期组的ＧｎＲＨ值显著低于对照组（Ｐ＜０．０５）。对闭经组进行垂体兴奋试验表明，其垂体未发生器质性病变。用ＲＩＡ法测定长月经周期组、短月经周期组和对照组唾液基础雌二醇（Ｅ_２）、孕酮（Ｐ）浓度。结果表明，长、短周期组Ｅ_２和Ｐ浓度均低于对照组（Ｐ＜０．０５）。
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| 关 键 词： | 运动性闭经，运动性月经失调，RIA，β－EP，GnRH，LH，FSH，E_2，P |
Research on Hypothalamus-Pituitary-Ovary Endocrinic Changes in Women Athletes with Menstrual Disorder |
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| Cui Liping,Tong Qiliang,et al.Research on Hypothalamus-Pituitary-Ovary Endocrinic Changes in Women Athletes with Menstrual Disorder[J].Chinese Journal of Sports Medicine,1996(1). |
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| Authors: | Cui Liping Tong Qiliang |
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| Institution: | Beijing University of Physical Education |
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| Abstract: | In order to investigate the mechanism of athletic amenorrhea and athletic menstrual disorder,fifty-three women athletes including 6 amenorrhea(r),10 short menstrual cycle(SMC),17 long menstrual cycle(LMC)and 20 normal menstruation(NM)were studied.The concentration of β-endorphin(β-EP),gonadotropin-releasing hormone(GnRH),Iuteal hormone(LH)and follicle-stimulating hormone(FSH)in plasma were measured by using radioimmunoassay(RIA)in Ar,LMC and NM.The results indicated that GnRH value of Ar and LMC was significantly lower than that of NM(p<0.05).Pituitary excited experiment in Ar showed that there was no organic disease in pituitary.The basic concentration of estradiol(E2)and progesterone(P)in saliva was measured by RIA in LMC SMC and NM.The concentration of E2 and P in LMC and SMC was significantly lower than that in NM(p<0.05). |
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| Keywords: | athletic amenorrhea athletic menstrual disorder RIA FSH LH GnRH E2 |
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