BOPINDOLOL: LONG-TERM EFFECTS ON BLOOD PRESSURE, RENAL FUNCTION, PLASMA RENIN ACTIVITY, AND PLASMA ALDOSTERONE IN MILD-TO-MODERATE ESSENTIAL HYPERTENSION |
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| Authors: | J. SHOHAT M. MODAN Professor. J.B. ROSENFELD |
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| Affiliation: | Nephrology Unit, Beilinson Medical Center, Petah Tikva, Israel. |
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| Abstract: | Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg. In 86.7% of the patients diastolic blood pressure was reduced by 10 mmHg or more, or lowered to below 90 mmHg, already during the first 4 wk of treatment. Inulin clearance decreased by 10%; PAH and creatinine clearance, blood urea nitrogen, and serum creatinine were unchanged. |
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| Keywords: | bopindolol hypertension plasma aldosterone plasma renin activity renal blood flow glomerular filtration rate |
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