| 用正交法考察天林在输液中的稳定性 |
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| 引用本文： | 梁健健,王娟.用正交法考察天林在输液中的稳定性[J].中国药房,2001,12(6):369-370. |
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| 作者姓名： | 梁健健 王娟 |
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| 作者单位： | 广州市第一人民医院临床药学室, |
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| 摘 要： | 目的 :在4℃、25℃、37℃下考察天林与不同 pH值的5 %葡萄糖注射液 (5 %GS)、葡萄糖氯化钠注射液 (GNS)、小儿维持液注射液在不同时间下的配伍稳定性。方法 :采用正交试验的方法 ,将天林用以上3种输液配成不同pH值的9份溶液 ,按4因素、3水平进行L9(34)正交试验 ,然后用紫外分光光度法测定各配伍液中天林的含量变化。结果 :配伍液在上述各温度、pH值输液中 ,0h～8h内天林的含量均无显著性变化。结论 :天林可与上述3种输液配伍。
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| 关 键 词： | 天林 正交法 输液 稳定性 |
| 文章编号： | 1001-0408（2001）06-0369-02 |
| 修稿时间： | 2000年11月8日 |
Observation of the
Stability of Mezlocillin Sodium in Infusion Fluids Using Orthogonal Test |
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| LIANG Jianjian,WANG Juan.Observation of the
Stability of Mezlocillin Sodium in Infusion Fluids Using Orthogonal Test[J].China Pharmacy,2001,12(6):369-370. |
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| Authors: | LIANG Jianjian WANG Juan |
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| Abstract: | OBJECTIVE： To observe the stability of mezlocillin sodium in 5％ glucose injection， glucose and sodium chloride injection and maintain solution for infants injection with different pH， over different periods and at 4℃ ， 25℃ ， 37℃ .METHODS： 9 solutions with different pH were made up by mezlocillin sodium and above-mentioned infusion fluids， according to 4 factors and 3 levels to make L9（34） orthogonal test.Then determination of mezlocillin sodium in each solution was carried out with ultraviolet spectrophotometry.RESULTS： The contents of mezlocillin sodium in above-mentioned solutions with different pH and at different temperature have not changed obviously over 0h-8h.CONCLUSION： Mezlocillin sodium is compatible with above-mentioned solutions. |
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| Keywords: | mezlocillin sodium orthogonal test infusion fluid stability |
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