| 复发-缓解型多发性硬化联络纤维定量DTI改变 |
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| 引用本文： | 周福庆,龚洪翰,庄莹,姜建,曾献军.复发-缓解型多发性硬化联络纤维定量DTI改变[J].临床放射学杂志,2011,30(1). |
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| 作者姓名： | 周福庆 龚洪翰 庄莹 姜建 曾献军 |
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| 作者单位： | 1. 南昌大学第一附属医院影像科,江西,330006
2. 南昌市第二医院内科,江西,330003 |
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| 摘 要： | 目的探讨复发-缓解型多发性硬化(RRMS)患者联络纤维定量扩散张量成像(DTI)改变。资料与方法选择低病灶负荷RRMS患者20例,年龄和性别相匹配的健康自愿者20名为对照进行MRI扫描,获取常规MRI图像和DTI图像,分别进行测量分析,比较RRMS患者和健康对照组联络纤维主要纤维束:上枕-额束、下枕-额束、钩束、下纵束、上纵束的部分各向异性指数(FA)值和平均扩散系数(MD)值的变化。结果 RRMS组患者钩束(L:F=5.498,P=0.024;R:F=5.158,P=0.029)、下纵束(L:F=8.267,P=0.007;R:F=5.108,P=0.03)、胼胝体/下枕-额束伴行部分(L:F=5.669,P=0.022;R:F=7.162,P=0.011)、下枕-额束/下纵束伴行部分(L:F=4.521,P=0.04;R:F=5.437,P=0.025)的FA值较健康对照组低,差异有统计学意义;RRMS组患者下纵束(L:F=5.012,P=0.031;R:F=5.48,P=0.025)、下枕-额束/下纵束伴行部分(L:F=8.318,P=0.006;R:F=12.882,P=0.00094)、胼胝体/下枕...
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| 关 键 词： | 多发性硬化 扩散张量成像 联络纤维 部分各向异性指数 |
Quantitative Diffusion Tensor Imaging of Association Fibers in RRMS |
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| ZHOU Fuqing,GONG Honghan,ZHUANG Ying,et al..Quantitative Diffusion Tensor Imaging of Association Fibers in RRMS[J].Journal of Clinical Radiology,2011,30(1). |
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| Authors: | ZHOU Fuqing GONG Honghan ZHUANG Ying |
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| Institution: | ZHOU Fuqing,GONG Honghan,ZHUANG Ying,et al.Department of Radiology,The First Affiliated Hospital,Nanchang University,Nanchang,Jiangxi,330006,P.R.China |
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| Abstract: | Objective To describe the change of quantitative diffusion tensor imaging(DTI) values of association fibers in patients with relapsing remitting multiple sclerosis(RRMS). Materials and Methods Twenty RRMS patients with lower lesion load,and 20 gender/age matched healthy persons were selected in the study. Conventional magnetic resonance imaging(cMRI) and DTI was performed,than fractional anisotropy(FA)/ mean diffusivity(MD) of the major fiber bundle in association fibers:superior fronto-occipital fasciculus... |
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| Keywords: | Multiple sclerosis Diffusion tensor imaging Association fibers Fractional anisotropy |
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