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外伤性颅骨缺损修复前、后局部脑血流变化的研究
引用本文:李鑫,李晶,徐珑,李京生. 外伤性颅骨缺损修复前、后局部脑血流变化的研究[J]. 北京医学, 2010, 32(5): 351-354
作者姓名:李鑫  李晶  徐珑  李京生
作者单位:首都医科大学附属北京天坛医院神经外科,100050;首都医科大学附属北京天坛医院手术室,100050
摘    要:目的探讨颅骨修补术对外伤性颅骨缺损患者脑血流动力学和神经症状的影响。方法对14例外伤性颅骨缺损患者颅骨修补前后多个时间点行脑SPECT检查,分别为术前、术后7d及术后10~24个月(平均1.5年)测量患者卧位时脑血流量,行手术前后自身对照分析,并且对其神经症状变化情况进行随访。结果术后18个月9例患者神经症状得到明显改善。患者行卧位SPECT检查发现颅骨修补术后7d局部脑血流量明显好于术前脑血流量,但5例患者术后10~24个月SPECT均发现相应部位脑血流量较术后7d和术前脑血流量有所下降。结论颅骨修补术后可改善脑血流量,同时有利于神经功能的恢复。

关 键 词:颅骨修补术  脑血流量  单光子发射计算机断层扫描

The influence of cranioplasty on local cerebral blood flow in traumatic skull defect patients
LI Xin,LI Jing,XU Long,et al. The influence of cranioplasty on local cerebral blood flow in traumatic skull defect patients[J]. Beijing Medical Journal, 2010, 32(5): 351-354
Authors:LI Xin  LI Jing  XU Long  et al
Affiliation:LI Xin,LI Jing,XU Long,et al(Department of Neurosurgery,Beijing Tiantan Hospital,Beijing 100050)
Abstract:Objective To investigate the effect of cranioplasty on local blood flow and neurological symptoms of patients with traumatic skull defect.Methods Fourteen patients in whom craniotomy operations had been performed underwent a meticulous quantitative study of local blood flow,as assessed by SPECT in supine positions respectively before operation,one week and/or average 1.5 year after operation.We also analyzed neurological symptoms at the same time.Results The neurological symptoms of 9 patients were improved...
Keywords:Cranioplasty Cerebral blood flow(CBF) Single photon emission computed tomography(SPECT)  
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