痛性眼肌麻痹综合征的临床观察

目的：进一步提高痛性眼肌麻痹综合征的诊断准确性和疗效以及探讨其可能的病因。方法：对临床确诊的18例痛性眼肌麻痹综合征患者的起病情况，颅神经受损的表现。辅助检查结果进行分析。结果：本组患者主要以眼病为主的多颅神经损害的症侯群，脑脊液及神经影像学可有异常发现。结论：头痛或单一眼肌麻痹的患者应作相应的鉴别诊断以明确本病。可能的病因为与免疫反应有关的非特异性炎症。对类固醇激素治疗不恢复者可用促肾上腺皮质激素获得满意疗效。

Clinical observation of painful ophthalmoplegia

Objective To improve diagnoses and treatment of painful ophthalmoplegia syndrome and study possible etiology of the syndrome. Methods Eighteen cases with painful ophthalmoplegia syndrome diagnosed clinically were collected and their modes of onset, the involvement of the cranial nerves and the results of the special examinations were analyzed. Results The syndrome of multiple cranial nerves with ophthalmopathy were found. Cerebrospinal fluid and neuroimaging examinations may be abnormal. Conclusion The patients with headache or sigle ophthalmoplegia must be diagnosed with exclusion. Possible etiology of the syndrome is nonspecific inflammatory with immune reaction, besides, satisfactory effect of adrenocorticotrophic hormone is acquired after corticosteroid treatment has no effect.