小型猪与小鼠腮腺、泪腺、垂体超微结构的观察与比较

目的 研究小型猪及小鼠腮腺的超微结构特点,并将腮腺与泪腺、垂体的超微结构对比观察,旨为涎腺基因治疗转基因表达的生物学特性提供腺体形态学的依据.方法选用成年小型猪、昆明种小鼠各5只,分别取腮腺、泪腺、垂体进行超微结构观察.结果小型猪较小鼠的腮腺腺泡细胞内分泌颗粒密度大,质地均匀,细胞器少见,血管内皮细胞内有较多分泌颗粒存在.小型猪与小鼠泪腺超微结构均与各自腮腺相似,小型猪与小鼠垂体结构特点为细胞排列散在,细胞间充满血窦及毛细血管.结论小型猪腮腺腺泡细胞分泌颗粒多,其毛细血管内皮细胞中也可见较多分泌颗粒,提示这些分泌颗粒可能进入血液发挥内分泌功能.

Comparative ultrastructural study of parotid gland, lacrimal gland and pituitary gland between miniature pig and mouse

Objective To study the ultrastructure of parotid glands, lacrimal glands and pituitary glands between miniature pig and mouse. Methods Five adult miniature pigs and 5 mice were studied. Ultrastructure of their parotid glands, lacrimal glands and pituitary glands was observed. Results The secretary granules in acinar cell of miniature pig parotid glands showed higher density and more aequalis than those of mice. The cell apparatus in acinar cell of mouse parotid glands were more plentiful than those of miniature pigs. The secretary granules on blood vessel wall were richer in parotid gland of miniature pigs compared with mouse parotid gland. Lacrimal gland had the similar ultrastructure to parotid gland in these two animals. Many blood vessel antrums were found in pituitary glands of these two animals. Conclusions Compared with mouse parotid glands, there are more secretary granules in acinar cells and vascular endothelial cells in miniature pig parotid glands, which might enter blood stream and have function of endocrine secretion.