| 内皮素在先天性心脏病肺动脉高压中表达的研究 |
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| 引用本文： | 郑建杰,黄斌,耿希刚,李兆志. 内皮素在先天性心脏病肺动脉高压中表达的研究[J]. 中国地方病学杂志, 2001, 20(4): 311-312 |
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| 作者姓名： | 郑建杰 黄斌 耿希刚 李兆志 |
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| 作者单位： | 西安交通大学第一医院心脏外科 |
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| 摘 要： | 目的：探讨内皮素（ET）在先天性心脏病（简称先心病）室间隔缺损（简称室缺）伴肺动脉高压（简称肺高压）中的主其临床意义。方法：应用放射免疫均相竞争法直接测定15例先心病室缺伴肺高压患者血浆中ET的表达，并与先心病室缺无肺高压的患者组作对照，结果：肺高压的先心病患者血浆中的ET水平显著高于无肺高压的先心病患者。结论：ET与先心病室缺伴肺高压的发生，发展有着极其密切的关系。
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| 关 键 词： | 内皮素 先天性心脏病 室间隔缺损 肺动脉高压 |
| 文章编号： | 1000-4955(2001)04-0311-02 |
| 修稿时间： | 2000-06-22 |
Expression of plasma endothelin in pulmonary hypertesion caused by ventricular septal defect of congenital heart |
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| ZHENG Jian-jie,HUANG Bin,GENG Xi-gang,et al. Expression of plasma endothelin in pulmonary hypertesion caused by ventricular septal defect of congenital heart[J]. Chinese Jouranl of Endemiology, 2001, 20(4): 311-312 |
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| Authors: | ZHENG Jian-jie HUANG Bin GENG Xi-gang et al |
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| Abstract: | Objective To detect endothelin (ET) in plasmal of ventricular septal defect (VSD) of contenital heart disease (CHD) with pulmonary hypertension (PH) and discuss its significance.Methods The levels of plasmal ET were measured by Radiommunoassary 15 CHD with PH and 15 CHD without PH of control groups.Results Plasma ET were markedly increased in patient with PH.Conclusions ET play an important role in formation of PH caused by CHD. |
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| Keywords: | Endothelin Congenital Ventricular septal defect Plumonary hypertension |
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