Abstract: | Large ulcerated lesions of the oral cavity may be benign or malignant, and often the oral and maxillofacial surgeon is asked to differentiate between the two. Biopsy is recommended in all suspected lesions. However, occasionally the original histologic impression of a malignant neoplasm is not confirmed by the clinical behavior of the lesion. This report describes such a case and emphasizes the role of light microscopy, immunohistochemistry, and electron microscopy in the evaluation of such lesions. |