Pathogenesis of delayed radiation injury in the rat spinal cord after X-ray irradiation |
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| Authors: | Hidehito Miyagawa Junko Yokofujita Riki Okeda Toshihiko Kuroiwa |
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| Abstract: | The pathogenesis of delayed radiation injury was examined experimentally. Exposure fields in the thoracic and lumbar spinal cords of 54 adult female specific pathogen-free Wistar rats were X-ray irradiated. The rats were observed clinically and pathologically for up to 6 months after irradiation and the relationships between the chronological progress of paralysis and pathological findings and between vascular and parenchymal changes were analyzed by reconstructing serial spinal cord sections. |
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| Keywords: | delayed radiation injury endothelial cell injury spinal cord spongiosis |
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