血管内支架结构截面形状的生物力学实验

血管内支架置入体内后会影响血流动力学和血管壁剪切应力等生物力学耦合作用。分析支架杆件扩张受力弯曲的梯形截面比例系数，分别对二维支架梯形截面结构进行血管壁接触和血液流场流固耦合数值计算实验。结果显示，支架结构梯形截面比例系数为4时可减小支架对血管壁的接触应力，并改善支架表面的血流动力学状况。这可以避免支架置入后对血管壁形成的应力受损，显著减低支架表面血栓沉积的再狭窄率，对于血管内支架的设计具有重要的指导意义。

Biomechanics experiment addressing cross-section shape of intravascular stent structure

After clinical intravascular implantation, stent has biomechanical coupling effect on hemodynamic and vessel wall shear stress. Here, materials mechanics is used to analysis the design about coefficient of trapezoidal cross-section ratio of stent structure during stent expanding by bend; trapezoidal cross-section of two-dimensional stent structure is numerical simulated both in the blood vessel wall contact experiment and in fluid-solid coupling experiment in the blood flow field. The results showed that the structure optimization of trapezoid cross-section stent can reduce the coefficient of the stent contacts the vessel wall stress and improve hemodynamics conditions on stent surface. This can be avoided blood vessel wall damage caused by stress, and owned a significant reduction on restenosis rate with thrombosis deposition in the surface of stent. It has great guiding significance on the stent design.