| 1999至2008年高血压专科住院患者病因构成的分析 |
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| 作者姓名： | Li NF Lin L Wang L Wang XL Zu FY Zhang DL Chang GJ Zhang YM Zhou KM Guli N Li T Hu JL Kong JQ Wang MH Luo Q |
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| 作者单位： | 新疆维吾尔自治区人民医院高血压科新疆维吾尔自治区高血压研究所,乌鲁木齐,830001 |
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| 基金项目： | 新疆维吾尔自治区科技基础条件平台建设项目 |
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| 摘 要： | 目的 分析1999至2008年新疆维吾尔自治区人民医院高血压专科住院患者病因构成及演变趋势.方法 采用回顾性研究方法 ,分析10年间7809例高血压专科住院患者的病因构成及在各年度分布情况,并对变化趋势进行分析.结果 (1)7809例高血压专科住院患者中原发性高血压5867例,占75.1%,继发性高血压1942例,占24.9%.(2)2008年和1999年继发性高血压所占的比例分别为39.3%(665/1692)、9.5%(32/338).10年间继发性高血压所占的比例逐年升高(χ2=387.621,P＜0.001＝.病因构成中,睡眠呼吸暂停综合征(OSAS)2008年占20.3%(343/1692),1999年占0.6%(2/338)(χ2=304.025,P＜0.001＝;原发性醛固酮增多症(PA)2008年占5.3%(89/1692),1999年占2.9%(10/338)(χ2=42.845,P＜0.001＝;其他病因所占比例变化较小.(3)2004至2008年PA合并OSAS比例逐年升高(χ2=26.376,P＜0.001＝,PA中OSAS占23.9%(65/272),OSAS中PA占6.7%(65/963).结论 1999至2008年高血压住院患者中,继发性高血压所占的比例逐年升高.在继发性高血压中,OSAS、PA所占的比例最高,同时应注意OSAS与PA两种继发性因素可能并存.
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| 关 键 词： | 高血压 病因学 |
Etiology analysis for hospitalized hypertensive patients: 10 years report from the department of hypertension (1999 - 2008) |
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| Li NF,Lin L,Wang L,Wang XL,Zu FY,Zhang DL,Chang GJ,Zhang YM,Zhou KM,Guli N,Li T,Hu JL,Kong JQ,Wang MH,Luo Q.Etiology analysis for hospitalized hypertensive patients: 10 years report from the department of hypertension (1999 - 2008)[J].Chinese Journal of Cardiology,2010,38(10):939-942. |
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| Authors: | Li Nan-fang Lin Li Wang Lei Wang Xin-ling Zu Fei-ya Zhang De-lian Chang Gui-juan Zhang Yan-min Zhou Ke-Ming Guli Nuer Li Tao Hu Jun-li Kong Jian-qiong Wang Men-hui Luo Qin |
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| Institution: | Department of Hypertension, Hypertension Institute of Xinjiang Uygur Autonomous Region, Urumuqi 830001, China. lnanfang2009@hotmail.com |
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| Abstract: | Objective To analyze etiology of hospitalized hypertensive patients in the department of hypertension from 1999 to 2008. Methods This retrospective study was performed to analyze the etiology of hospitalized hypertensive patients in department of hypertension and to show the distribution change of hypertension from 1999 to 2008. Results ( 1 ) There were 5867 ( 75. 1% ) patients with essential hypertension and 1942 (24. 9% ) patients with secondary hypertension (SH). (2) The prevalence rate of SH increased significantly during the 10 years (χ2 = 387.621 ,P ＜ 0.001 ) and was higher in 2008 than in 1999 (39. 3% vs. 9. 5% , P ＜ 0. 05 ). The prevalence of obstructive sleep apnea syndrome (OSAS) and primary aldosteronism (PA) in 2008 increased 38.3 and 1.8 times respectively than in 1999 (χ2 =304. 025 ,P ＜0. 001; χ2 =42. 845 ,P ＜0. 001 ) and other SH remained unchanged. ( 3 ) The prevalence of PA complicated with OSAS increased significantly in recent five years ( χ2 = 26.376, P ＜0. 001 ). Incidence of OSAS was 23.9% in PA patients and incidence of PA was 6. 7% in OSAS patients. Conclusions With the insights gained on hypertension mechanism and the development of new diagnostic technology, percent of diagnosed SH increased remarkably in recent years in hospitalized hypertensive patients in our department of hypertension. OSAS and PA are the leading causes of SH. |
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| Keywords: | Hypertension Etiology |
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