Povidone iodine in the treatment of adenoviral conjunctivitis in infants |
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Authors: | Zuhal Özen Tunay Ozdemir Ozdemir Ikbal Seza Petricli |
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Institution: | 1. Department of Ophthalmology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey and;2. Department of Ophthalmology, Etlik Zubeyde Hanim Maternity and Research Hospital, Ankara, Turkey |
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Abstract: | Context: Adenoviral conjunctivitis.Objective: To examine the effects of conjunctival irrigation with povidone iodine in infants with adenoviral conjunctivitis. Material and methods: An outbreak of adenovirus conjunctivitis occurred between September and December 2012 at the neonatal intensive care unit of our hospital. Forty-three infants with adenoviral conjunctivitis were examined in this study. Thirty-five eyes of 35 infants who had detailed ophthalmological examination and clinical scoring were included. The conjunctiva of 15 infants (Group 1) were irrigated with povidone iodine 2.5% solution and then treated with preservative-free artificial tears and preservative-free antibiotic drops. Twenty infants (Group 2) were treated only with the same drops with the same posology, without conjunctival irrigation with povidone iodine. Patients were examined two times a week until the complete recovery. Lid edema, conjunctival chemosis, fragility of conjunctival vasculature, pseudomembrane formation, and corneal involvement were scored clinically. Results: Twenty patients (57%) were female and 15 patients (43%) were male and mean age was 3.1 months (ranged from 1 to 4 months). No relation was found between gender and clinical scores. Statistically significant lower clinical scores were obtained from Group 1. The median recovery time was earlier in Group 1 (7?d) than Group 2 (12?d) (p?=?0.001). Conclusion: Conjunctival irrigation with 2.5% povidone iodine is effective in the treatment of adenoviral conjunctivitis in infants. |
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Keywords: | Adenovirus epidemic keratoconjunctivitis infants povidone iodine pseudomembrane |
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