| 海岛轮环藤碱-N-氧化物的制备和结构 |
| |
| 引用本文： | 赖盛,赵同芳,王宪楷,志津里芳一,山村庄亮. 海岛轮环藤碱-N-氧化物的制备和结构[J]. 药学学报, 1993, 28(7): 557-560 |
| |
| 作者姓名： | 赖盛 赵同芳 王宪楷 志津里芳一 山村庄亮 |
| |
| 作者单位： | 华西医科大学药学院，华西医科大学药学院，华西医科大学药学院，庆应义塾大学理工学部，庆应义塾大学理工学部 成都 610041，成都 610041，成都 610041，日本横滨 223，日本横滨 223 |
| |
| 摘 要： | Oxidation of insularine (Ⅰ) with m-chloroperbenzoic acid yielded four insularine-N-oxides. Two of them are identical in every respect with our insularine-2β-N-oxide (Ⅱ) and insularine-2'β-N-oxide (Ⅲ), two rare examples of naturally occurring head-to-tail bisbenzyliso-quinoline N-oxides newly isolated from Cyclea sutchnenensis, which confirmed the structures of the two novel natural N-oxides. The other two are new. compounds and their structures have been established as insularine-2'α-N-oxide (Ⅳ) and insularine-2β-2'β-N, N-dioxide (Ⅴ), on the basis of spectral data (UV, IR. 1HNMR, NOEDS AND MS) analysis.
|
| 关 键 词： | 海岛轮环藤碱 海岛轮环藤碱-N-氧化物 双苄基异喹啉生物碱 四川轮环藤 |
| 收稿时间： | 1992-08-28 |
PREPARATION AND STRUCTURAL ELUCIDATION OF INSULARINE-N-OXIDES |
| |
| S Lai,TF Zhao,XK Wang,Y Shizuri and S Yamamura. PREPARATION AND STRUCTURAL ELUCIDATION OF INSULARINE-N-OXIDES[J]. Acta pharmaceutica Sinica, 1993, 28(7): 557-560 |
| |
| Authors: | S Lai TF Zhao XK Wang Y Shizuri S Yamamura |
| |
| Abstract: | Oxidation of insularine (Ⅰ) with m-chloroperbenzoic acid yielded four insularine-N-oxides. Two of them are identical in every respect with our insularine-2β-N-oxide (Ⅱ) and insularine-2'β-N-oxide (Ⅲ), two rare examples of naturally occurring head-to-tail bisbenzyliso-quinoline N-oxides newly isolated from Cyclea sutchnenensis, which confirmed the structures of the two novel natural N-oxides. The other two are new. compounds and their structures have been established as insularine-2'α-N-oxide (Ⅳ) and insularine-2β-2'β-N, N-dioxide (Ⅴ), on the basis of spectral data (UV, IR. 1HNMR, NOEDS AND MS) analysis. |
| |
| Keywords: | Insularine Insularine-X-oxides Bisbenzylisoquinoline alkaloids Cyclea sutchuenensis |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《药学学报》浏览原始摘要信息 |
|
点击此处可从《药学学报》下载全文 |
|
