| к-硒化卡拉胶对免疫抑制小鼠淋巴细胞增殖及抗体形成细胞的影响(英文) |
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| 引用本文： | 张罗修,贾永锋,干翠宝,曹致芳. к-硒化卡拉胶对免疫抑制小鼠淋巴细胞增殖及抗体形成细胞的影响(英文)[J]. 药学学报, 1993, 28(8): 614-618 |
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| 作者姓名： | 张罗修 贾永锋 干翠宝 曹致芳 |
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| 作者单位： | 上海医科大学药学院药理教研室,上海200032 |
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| 摘 要： | 硒化卡拉胶是一个新的含硒有机化合物。本文主要观察它对环磷酰胺引致免疫抑制小鼠的淋巴细胞增殖及抗体形成细胞(PFC)的影响。研究结果表明,环磷酰胺可明显抑制小鼠淋巴细胞增殖及抗体形成细胞数。硒化卡拉胶2或12 mg/kg po qd×20～40可明显刺激免疫抑制小鼠的淋巴细胞增殖或抗体形成细胞,但大剂量硒化卡拉胶(72 mg/kg)不能显示稳定的刺激作用,在某些条件下反而转向抑制作用。
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| 关 键 词： | 硒化卡拉胶 淋巴细胞增殖 抗体形成细胞 |
| 收稿时间： | 1992-06-19 |
EFFECTS OF κ-SELENOCARRAGEENAN ON LYMPHOCYTE PROLIFERATION AND ANTIBODY PRODUCTIVE CELLS IN IMMUNOSUPPRESSED MICE |
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| LX Zhang,YF Jia,CB Gan and ZF Cao. EFFECTS OF κ-SELENOCARRAGEENAN ON LYMPHOCYTE PROLIFERATION AND ANTIBODY PRODUCTIVE CELLS IN IMMUNOSUPPRESSED MICE[J]. Acta pharmaceutica Sinica, 1993, 28(8): 614-618 |
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| Authors: | LX Zhang YF Jia CB Gan ZF Cao |
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| Abstract: | Two flavonoids were isolated from the leaves of Glycyrrlaiza uralensisFisch (Licorice,Leguminosae).On the basis of physico-chemical properties and spectroscopy(UV,1HNMR and MS),a new compound was elucidated as 3,5,7,4'-tetrahydroxy-3'-methoxy-6-isorenyl flavone (gancaonin P-3'-methylether)and another know compound was identified as 8-C-prenyleriodictyol. |
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| Keywords: | Cyclophosphamide Plaque forming cells Lymphocyte proliferation κ-Selenocarrageenan |
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