| 超声造影剂灌注曲线斜率与流速相关性的初步研究 |
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| 引用本文： | 路晶,周翔,谢明星,王新房,吕清.超声造影剂灌注曲线斜率与流速相关性的初步研究[J].中国医学影像技术,2007,23(11):1717-1720. |
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| 作者姓名： | 路晶 周翔 谢明星 王新房 吕清 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院超声影像科,湖北省分子影像重点实验室,湖北,武汉,430022 |
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| 摘 要： | 目的探讨超声Flash-replenishment成像技术中超声造影剂灌注曲线斜率与流速的相关性。方法采用自制动力泵-超滤纤维系统模拟器官微循环血流动力学,建立微循环血流模型。连续输注20ml造影剂SonoVue(1∶3稀释),应用FR成像技术,分别测定微循环流速为0.25mm/s、0.5mm/s、1mm/s、2mm/s、4mm/s、8mm/s时造影剂的再灌注曲线斜率β,对β值与实际流速进行相关性分析。结果微循环流速为2～8mm/s时β值与实际流速相关性良好,r=0.97;微循环流速为0.25～1mm/s,二者相关性较差,r=0.44。结论微循环流速低于1mm/s以下时,造影剂再灌注曲线的β值与实际流速相关性差,故低流速状态下造影剂的灌注定量方法有待进一步研究。
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| 关 键 词： | 超声造影剂 连续灌注 |
| 文章编号： | 1003-3289（2007）11-1717-04 |
| 收稿时间： | 2007-06-06 |
| 修稿时间： | 2007-09-04 |
Correlation between slope rate of flash-replenishment curve of ultrasonic contrast imaging and the flow velocity in the model of microcirculatory dynamics: initial exploration |
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| LU Jing,ZHOU Xiang,XIE Ming-xing,WANG Xin-fang and LV Qing.Correlation between slope rate of flash-replenishment curve of ultrasonic contrast imaging and the flow velocity in the model of microcirculatory dynamics: initial exploration[J].Chinese Journal of Medical Imaging Technology,2007,23(11):1717-1720. |
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| Authors: | LU Jing ZHOU Xiang XIE Ming-xing WANG Xin-fang and LV Qing |
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| Institution: | Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China;Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China;Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China;Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China;Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China |
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| Abstract: | |
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| Keywords: | Flash-replenishment |
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