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紫芝中的一个新三萜
引用本文:刘超,陈若芸. 紫芝中的一个新三萜[J]. 中草药, 2010, 41(1): 8-11
作者姓名:刘超  陈若芸
作者单位:中国医学科学院北京协和医学院,药物研究所,中草药物质基础与资源利用教育部重点实验室,北京,100050
基金项目:科技部科技基础性工作专项(2007Fy130100)
摘    要:目的研究紫芝Ganoderma sinense子实体的化学成分。方法通过反复硅胶、凝胶柱色谱进行分离纯化,利用多种波谱技术鉴定化合物的结构。结果分离鉴定了4个化合物,分别为紫芝酸(sinensoic acid,1)、cere-broside D(2)、poke-weed cerebroside(3)、泥湖鞘鞍醇(hemisceramide,4)。结论化合物1为新化合物,命名为紫芝酸(sinensoic acid),其余化合物均为首次从灵芝属真菌中分离得到。

关 键 词:紫芝  三萜  sinensoicacid  脑苷  
收稿时间:2009-07-15

A new triterpene from fungal fruiting bodies of Ganoderma sinense
LIU Chao and CHEN Ruo-yun. A new triterpene from fungal fruiting bodies of Ganoderma sinense[J]. Chinese Traditional and Herbal Drugs, 2010, 41(1): 8-11
Authors:LIU Chao and CHEN Ruo-yun
Affiliation:LIU Chao,CHEN Ruo-yun(Key Laboratory of Bioactive Substances , Resources Utilization of Chinese Herbal Medicine,Ministry of Education,Institute of Materia Medica,Chinese Academy of Medical Sciences , Peking Union Medical College,Beijing 100050,China)
Abstract:Objective To study the chemical constituents from the fungal fruiting bodies of Ganoderma sinense.Methods Individual constituents,isolated and repeatedly purified on silica gel and Sephadex LH-20 column chromatography,were identified by physicochemical constants and structurally elucidated by spectral methods.Results Four compounds were isolated and identified as: sinensoic acid(1),cerebroside D(2),poke-weed cerebroside(3),hemisceramide(4).Conclusion Compound 1 is a new compound,others are isolated from the...
Keywords:Ganoderma sinense Zhao  Xu et Zhang  triterpenes  sinensoic acid  cerebroside  
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