脑卒中后抑郁及干预治疗对神经功能康复的影响

目的观察脑卒中后抑郁及其干预治疗对神经功能缺损康复的影响。方法将90例首发脑卒中伴抑郁的患者随机分为3组，分别给子黛安神、阿米替林和安慰剂治疗，于治疗前、治疗后2、4周及3、6月用汉密顿抑郁量表(HAMD)、神经功能缺损评分表(CSS)检测。结果黛安神组和阿米替林组的HAMD和CSS评分在治疗后显著低于对照组。结论抗抑郁治疗可显著减轻脑卒中后抑郁及其对神经功能恢复的不利影响，有利于神经功能缺损的康复。

The effect of post-stroke depression and intervention on the rehabilitation of neurological function

Objective To investigate the effect of post - stroke depression and treatment on the rehabilitation of neurological function. Method90 consecutive depressed patients were randomly assigned to equally sized Deanxit, Amitriptyline and placebo group. Patients were assessed byHamilton depression scale(HAMD) and Chinese stroke scale before treatment and 2 weeks, 4 weeks, 3 months and 6 months after treatment.Result The value of HAMD and CSS of Deanxit and Amitriptyline group have a statisticly significant reduction after treatment compared withthe placebo group. Conclusion The antidepressant therapy could significantly decrease the post -sroke depression and promote functionalrecoverv.