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原发性肝癌术中放射治疗研究
引用本文:卢金利,杨芳,王作仁.原发性肝癌术中放射治疗研究[J].南方医科大学学报,2010,30(2):301.
作者姓名:卢金利  杨芳  王作仁
作者单位:1. 西安交通大学第一附属医院放疗科,陕西,西安,710061
2. 西安交通大学西区图书馆,陕西,西安,710061
基金项目:陕西省科技攻关项目(2005k09-G5)
摘    要:目的探讨原发性肝癌术中放疗的可行性和优点。方法利用放疗计划系统对16例肝癌患者,结合靶区剂量曲线分布情况和剂量体积直方图,进行术中放疗,并与三维适形放射治疗和PBT进行比较。结果肝癌术中放疗90%的剂量线均能包绕靶区体积,显著好于三维适形放射治疗。肝癌术中放疗治疗计划与PBT计划相似,但治疗费用明显低于PBT费用。结论肝癌术中放疗能使靶区剂量分布均匀,适形度好,同时也有效地保护了敏感器官,有望提高肿瘤靶区剂量及肿瘤局部控制率。

关 键 词:原发性肝癌  术中放疗  三维适形放疗  质子治疗  

Study of intra-operative radiotherapy in primary liver cancer
LU Jin-li,YANG Fang,WANG Zuo-ren.Study of intra-operative radiotherapy in primary liver cancer[J].Journal of Southern Medical University,2010,30(2):301.
Authors:LU Jin-li  YANG Fang  WANG Zuo-ren
Institution:LU Jin-li1,YANG Fang2,WANG Zuo-ren1 Department of Radiation Oncology,First Affiliated Hospital1,Western District Library2,Xi'an Jiaotong University,Xi'an 710061,China
Abstract:Objective To study the feasibility of intraoperative radiotherapy(IORT) in primary liver cancer.Methods Based on the target of dose curves,the dose-volume histogram(DVH) and cost of radiation equipment and radiation therapy,IORT was compared with protonbeam therapy(PBT) and 3DCRT in 16 patients with primary liver cancer using the therapy plan system(TPS).Results IORT had significantly better performance than 3DCRT to allow a target region surrounded by 90% of the dose lines.IORT was similar to protonbeam th...
Keywords:primary liver cancer  intra-operative radiotherapy  3-dimensional conformal radiotherapy  protonbeam therapy  
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