Rheumatoid arthritis and the era of biologic therapy |
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| Authors: | Anshuman P Malaviya Andrew J K ?st?r |
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| Affiliation: | (1) School of Clinical Medicine, University of Cambridge, Cambridge, UK;(2) Rheumatology Clinical Research Unit, E6, Level 6, Addenbrooke’s Hospital, Hills Rd, Cambridge, CB2 0QQ, UK |
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| Abstract: | Biologic disease modifying anti-rheumatic drugs have transformed the management of rheumatoid arthritis (RA) since their introduction
into clinical practice over a decade ago. Following large-scale clinical trials, a number of biologics, with different mechanisms
of action, have been licensed for the condition. In this review, we will summarise the current evidence for biologic use in
RA with an emphasis on their efficacy and tolerability. In addition, we will provide a commentary on the current limitations
and unmet needs in this area and discuss the future of biologic intervention. |
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