Rasburicase for hyperuricemia in hemolytic uremic syndrome |
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| Authors: | Acosta Alisa A Hogg Ronald J |
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| Affiliation: | (1) Division of Pediatric Nephrology, Department of Pediatrics, Scott & White Children’s Hospital/Texas A&M Health Science Center College of Medicine, 2401 South 31st Street, Temple, TX 76508, USA |
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| Abstract: | Background Acute kidney injury (AKI) with elevated serum uric acid (UA) levels has been reported in patients with hemolytic uremic syndrome (HUS). AKI is thought to result from tubular obstruction by UA crystals. Inducing a diuresis may ameliorate the oligoanuria in such patients. We describe a child with HUS in whom reducing UA with fluids and rasburicase appeared to accelerate the recovery of renal function. |
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