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Association between serotonin transporter gene polymorphism and anxiety-related traits.
Authors:S Katsuragi  H Kunugi  A Sano  T Tsutsumi  K Isogawa  S Nanko  J Akiyoshi
Affiliation:Department of Neuropsychiatry, Oita Medical University, Japan.
Abstract:BACKGROUND: Polymorphism in the serotonin transporter promoter gene has been recently reported to be associated with the personality trait known as anxiety-related traits. We have attempted to replicate these findings in 101 healthy Japanese subjects. METHODS: The personality traits of the subjects were assessed with the tridimensional personality questionnaire. RESULTS: An association was observed in the present study between individuals grouped according to the transporter gene and harm avoidance scores. CONCLUSIONS: These data supported that there was an association between the serotonin transporter gene and anxiety.
Keywords:
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