50岁以上精神分裂症患者的认知特征

目的：探讨50岁以上精神分裂症患者的认知损害特征及其影响因素。方法：对60例50岁以上精神分裂症患者和40例正常人进行了威斯康星卡片分类测验（WCST）、韦氏成人智力量表（WAIS－R）、韦氏记忆量表（WMS）、语言流利性测验（LF）、手指敲击测验（FTT）、简明精神病评定量表（BPRS）及阴性症状评定量表（SANS）等测查。结果：患者组的所有认知测查结果均较正常人显著减退，且年龄、病程、阴性症状及亚型对患者认知功能有显著影响。结论：年龄较大、病程较长、阴性症状较重及非偏执型的精神分裂症患者认知缺损严重。

Clinical analysis of cognitive function in schizophrenic patients with age being more than 50 years old

Objective:To explore the characteristics and influence factors of cognitive impairment in schizophrenic patients (age≥50y).　Method:Sixty schizophrenic patients and 40 normal controls were examined with Wisconsin card sorting test (WCST),Wechsler adult intelligence scale (WAIS-R),Wechsler memory scale (WMS),the language fluency test (LF),the finger tapping test (FTT),the brief psychiatric rating scale (BPRS) and the scale for the assessment of negative symptoms (SANS).　Results:The cognitive functions in schizophrenia were reduced more significantly than that in controls.Age,illness duration,negative symptoms and subtype of diagnosis were associated with cognitive deficits in schizophrenia.　Conclusion:The senile schizophrenic patients with long duration sever negative symptoms and non-paranoid type may have more obvious cognitive deficits.