Pharmacological Studies on Leaves of Withania somnifera. |
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| Authors: | S Sudhir R D Budhiraja G P Miglani B Arora L C Gupta K N Garg |
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| Institution: | 4/8 FM, Medical College, Rohtak-124001 (Haryana), India. |
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| Abstract: | Anti-inflammatory activity and protective effect against CCl (4)-induced hepatotoxicity of alcoholic extract of leaves of WITHANIA SOMNIFERA have been assessed. The leaves were found to possess marked effects in subacute inflammation and hepatotoxicity. A comparison of the anti-inflammatory properties revealed the extract at 1 g/kg dose to be as active as 50 mg/kg of phenylbutazone and 10 mg/kg of hydrocortisone. The protective effect of the extract at 1 g/kg dose against CCl (4)-induced hepatotoxicity was comparable to 10 mg/kg of hydrocortisone. |
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