强直性脊柱炎骨质疏松128例临床分析

目的对强直性脊柱炎骨质疏松患者的临床表现和诊治情况进行分析探讨,为今后的临床诊治与预防工作提供可靠的参考依据。方法选强直性脊柱炎合并骨质疏松患者128例和同期健康体检者80例作为研究对象,分别为观察组和健康组,对其展开相应的骨密度以及骨代谢指标检测并对比分析结果。结果观察组患者腰椎、股骨颈、三角区以及转子部骨密度较健康组明显降低(P<0.05);观察组患者的BGP、PTH以及尿D-Pyr水平与健康组比较差异显著(P<0.05)。结论强直性脊柱炎早期即可出现骨质疏松,而由此导致的骨折发生率明显增加,骨质疏松主要与骨吸收增加有关,临床应给予关注。

Clinical Analysis of 128 Patients with Ankylosing Spondylitis Osteoporosis

Objective Clinical manifestations,diagnosis and treatment of conditions in patients with ankylosing spondylitis were analyzed and studied,for future clinical diagnosis and the prevention work to provide reliable reference.Method 128 patients with ankylosing spondylitis and osteoporosis and 80 healthy persons during the same period were selected as the research object,respectively,into the observation group and the healthy group.They were expanded the appropriate bone mineral density and bone metabolism to detect and comparative analysis of the result.Results lumbar spine,femoral neck,triangle and rotor bone mineral density in the observation group was significantly lower compared to the healthy group(P<0.05);BGP,PTH and urinary D-Pyr levels in the observation group has significant difference compared with healthy controls(P<0.05).Conclusion Ankylosing spondylitis can occur in the early time of osteoporosis,and result fracture incidence increased significantly.Osteoporosis was related to increased bone resorption,it should be given attention in clinical.