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曲唑酮与阿米替林治疗焦虑性神经症的对照研究
引用本文:郑占杰 王骞 王立涛 田博. 曲唑酮与阿米替林治疗焦虑性神经症的对照研究[J]. 精神医学杂志, 2001, 14(4): 231-232
作者姓名:郑占杰 王骞 王立涛 田博
作者单位:郑占杰(266034,青岛市精神卫生中心)      王骞(266034,青岛市精神卫生中心)      王立涛(266034,青岛市精神卫生中心)      田博(266034,青岛市精神卫生中心)
摘    要:目的比较曲唑酮与阿米替林治疗焦虑性神经症的疗效和副反应.方法 64例符合CCMD-2-R诊断标准的焦虑性神经症患者,随机分为两组,应用曲唑酮(32例)、阿米替林(32例)治疗六周.采用焦虑自评量表(SAS)、Hamilton焦虑量表(HAMA)和副反应量表(TESS)评定疗效和副反应.结果曲唑酮与阿米替林治疗焦虑性神经症均有疗效,二者疗效相当(P>0.05).曲唑酮的副反应明显少于阿米替林(P<0.01).结论曲唑酮是治疗焦虑性神经症的安全、有效药物.

关 键 词:曲唑酮 阿米替林 焦虑性神经症 治疗

A comparative study of trazodone and amitriptyline in the treatment of patients with anxiety neurosis.
Zheng Zhanjie,Wang Qian,Wang Litao et al. Qing Dao Mental Health Centre,QingDao. A comparative study of trazodone and amitriptyline in the treatment of patients with anxiety neurosis.[J]. Journal of Psychiatry, 2001, 14(4): 231-232
Authors:Zheng Zhanjie  Wang Qian  Wang Litao et al. Qing Dao Mental Health Centre  QingDao
Affiliation:Zheng Zhanjie,Wang Qian,Wang Litao et al. Qing Dao Mental Health Centre,QingDao 266034
Abstract:Objective To compare the efficacy and side effects of trazodone and amitriptyline on patients with anxiety neurosis.Methods Sixty four patients met with the criteria of CCMD-2-R for anxiety neurosis were assigned randomly to trazodone or amitriptyline treatment for 6 weeks.Efficacy and side effects were measured with HAMD, SAS and TESS.Results Both drugs showed similar efficient in treating anxiety neurosis,however,trazodone had fewer side effects than amitriptyline.Conclusion Trazodone is a safe and efficient drug in treating anxiety neurosis.
Keywords:Deprssion Trazodone Amitriptyline
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