| Recombinant adeno-associated virus-mediated inhibiting of interleukin-4 expression in rat model of asthma |
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| 作者单位： | Department of Respiratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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| 基金项目： | This study was supported by a grant from the National Natural Science Foundation of China(No. 30300144). |
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| 摘 要： | Asthma is a chronic disease characterized by reversible airway obstruction, airway hyper- responsiveness, and inflammation of airways. Th2 cells, one sort of CD4+ T lymphocytes, are currently considered to play an important role in the chronic airway inflammation of asthma. Meanwhile, a number of laboratories have clearly established the importance of the Th2-derived cytokine interleukin-4 (IL-4) in mediating the airway inflammatory response. Anti-IL-4 therapy might be beneficial in treatme…
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| 关 键 词： | adeno-associated virus interleukin-4 asthma |
Recombinant adeno-associated virus-mediated inhibiting of interleukin-4 expression in rat model of asthma |
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| Authors: | CAO Yong XIONG Wei-ning XU Yong-jian ZHANG Zhen-xiang GAO Bao-an DU Chun-ling LU Jun-yu YE Tao |
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| Abstract: | |
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| Keywords: | adeno-associated virus interleukin-4 asthma |
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