孕前及孕期甲状腺功能减退筛查的临床分析

目的探讨甲状腺功能减退与不良孕史的相关性及孕期甲状腺功能减退筛查的意义。方法选取2010年10月-2011年8月期间在我院门诊就诊的生育年龄妇女共243例,采用化学发光（CIA）进行甲状腺功能激素系列（TSH、FT4、TPOAb）测定。结果不良孕史中甲状腺功能低下所占比例明显高于无不良孕史组;亚临床甲状腺功能低下在临床上发生率相对较高。结论甲状腺功能减低与不良孕史有明显相关性;要重视亚临床甲状腺功能低下的发生;进行孕期甲状腺功能筛查很有必要。

Before and during pregnancy clinical analysis of hypothyrzoidism screening

Objective: To investigate the hypothyroidism associated with adverse pregnancy history and the relationship between the thyroid function duringpregnancy to decline screening significance.Methods: From 2010 October to 2011 August in our hospital outpatient women of childbearing age in all 243 cases,using a chemiluminescence(CIA) for thyroid function hormone series(TSH,FT4,TPOAb) determination.Results: Adverse pregnancy history of hypothyroidism proportion is obviously higher than that without adverse pregnancy history group;subclinical hypothyroidism in the clinical occurrence rate is relatively high.Conclusion:Hypothyroidism is associated with adverse pregnancy history have significant correlation;attention to subclinical hypothyroidism;thyroid function screening during pregnancy is necessary.