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IL—2/LAK与放,化疗联合治疗晚期恶性肿瘤
引用本文:许素玲 吉军. IL—2/LAK与放,化疗联合治疗晚期恶性肿瘤[J]. 新疆医科大学学报, 2000, 23(1): 41-43
作者姓名:许素玲 吉军
作者单位:附属肿瘤医院肿瘤防治研究所!新疆 乌鲁木齐 830054,附属肿瘤医院肿瘤防治研究所!新疆 乌鲁木齐 830054,附属肿瘤医院肿瘤防治研究所!新疆 乌鲁木齐 830054,附属肿瘤医院肿瘤防治研究所!新疆 乌鲁木齐 830054
摘    要:目的:探讨IL-/LAK细胞与放疗和/或化疗联合治疗晚期恶性肿瘤的价值。方法:本组共30例,其中单纯IL-2/LAK细胞治疗5例(包括2例TIL细胞胸腹腔灌注),IL-2/LAK细胞联合放疗18例(包括1例动脉灌注),IL-2/LAK细胞联合化疗4例)包括1例动态灌注),IK-2/LAK细胞联合放疗和化疗3例。结果:完全缓解率20.0%(6/30),总有效率50.0%(15/39),其中单纯IL-

关 键 词:IL-2/LAK细胞 恶性肿瘤 药物疗法 放射疗法

IL-2/LAK cells combination radiotherapy and chemotherapy in the treatmemt of advanced cancer
XU Su-ling,JI Jun,LIU Cheng-ming,et al. IL-2/LAK cells combination radiotherapy and chemotherapy in the treatmemt of advanced cancer[J]. Journal of Xinjiang Medical University, 2000, 23(1): 41-43
Authors:XU Su-ling  JI Jun  LIU Cheng-ming  et al
Abstract:Objective: To evaluate the results of IL-2/LAK cells combination radiotherapy and chemotherapy in the treatment of advanced cancer. Methods: 30 patients of advanced cancer were studied in this trial Of them, 5 patients treated by IL-2/LAK cells alone (2 of 5 patients received TIL cells), 18 patients received IL-2/LAK cells combination radiotherapy (1 of them received artery infusion), 4 patients recei-ved IL-2/ LAK cells combination chemotherapy (1 of them received artery infusion), and 3 patients received IL-2/LAK cells combination radiotherapy and chemotherapy. Results: The overall response rate was 50.0%, (15/30) with a complete response rate of 20.0% (1/5) in IL-2/LAK cells group only, and 56.0% (14/25 ) in combined group. Two patients with Kaposis's sarcoma achieved complete response. Conclusions: This result showed that IL-2/LAK cells for advanced carcinoma are effective, that IL-2/LAK cells combined with radiotherapy and (or) chemotherapy are conducive to good response rate.
Keywords:IL-2/LAK cells  radiotherapy  chemotherapy  combined treatment  malignant tumor
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