重型SARS合并MODS的临床救治初探

目的 探讨重型严重急性呼吸综合征(SARS)合并多器官功能障碍综合征(MODS)病例的发病特点、机制和治疗方法。方法 回顾性分析某院收治的54例重型SARS病例临床资料。结果 54例重型SARS患者均出现全身炎症反应综合征(SIRS)；29例(53．70％)并发MODS，死亡12例(41．38％)；器官损害以肺脏和心脏损害最常见，其次是脑、血液系统、肾、肝脏。结论 重型SARS患者出现MODS的主要原因是机体严重缺氧，故对其的救治应强调及时纠正缺氧状态；并需重视对多器官功能障碍的早期检查、诊断和治疗。

Preliminary analysis of clinical characteristics and treatment of serious type of SARS in patients with MODS

Objective To study the clinical characteristics, pathogenesis and treatment of the serious type of SARS in patients who suffered from multiple organ dysfunction syndrome (MODS). Methods Retrospective analysis was performed based on the clinical data of serious type of SARS in 54 patients with MODS in a hospital. Results All 54 SARS patients developed systemic inflammatory response syndrome (SIRS), 29 (53.70%) of whom developed MODS and the mortality of patients with MODS was 41.4%. Lung and heart were the most involved organs, the next were brain, blood system, kidney and liver. Conclusion Serious type of SARS is easily complicated with MODS, anoxia was the main cause of MODS, correcting anoxia at early stage is critical, and early exam, diagnosis and treatment of MODS should also be paid attention to.