| 灵芝孢子对2型糖尿病大鼠脑细胞线粒体Ca2+的影响 |
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| 引用本文： | 赵晓莲,齐淑芳,王柏欣,王淑秋,王跃新.灵芝孢子对2型糖尿病大鼠脑细胞线粒体Ca2+的影响[J].中国初级卫生保健,2005,19(12):98-99. |
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| 作者姓名： | 赵晓莲 齐淑芳 王柏欣 王淑秋 王跃新 |
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| 作者单位： | 佳木斯大学基础医学院,黑龙江,佳木斯,154007 |
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| 摘 要： | 目的 观察2型糖尿病大鼠脑细胞线粒体Ca^2＋变化，从而探讨灵芝孢子对上述指标的影响。方法用链尿佐菌素复制糖尿病大鼠模型．观察灵芝孢子对糖尿病大鼠细胞线粒体Ca^2＋的影响。结果模型组脑细胞线粒体Ca^2＋显著高于正常组和灵芝组（P〈0．05），差异有统计学意义。结论Ca^2＋参与脑细胞损伤。灵芝孢子粉对糖尿病大鼠脑组织具有保护作用。
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| 关 键 词： | 2型糖尿病 脑细胞线粒体Ca^2＋ 灵芝孢子 |
| 文章编号： | 1001-568X（2005）12-0098-02 |
| 收稿时间： | 2005-09-28 |
| 修稿时间： | 2005-09-28 |
The Effect of the Spores of Ganoderma Lucidum to Mitochondial Calciumin Brain Cellof Niddm Rats |
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| Zhao Xiaolian, Qi Shufang, Wang Yuexin,et al..The Effect of the Spores of Ganoderma Lucidum to Mitochondial Calciumin Brain Cellof Niddm Rats[J].Chinese Primary Health Care,2005,19(12):98-99. |
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| Authors: | Zhao Xiaolian Qi Shufang Wang Yuexin |
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| Institution: | Basic Medical College, Jiamusi University, Heilongjiang, Jia musi, 154007, PRC |
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| Abstract: | OBJECTIVE We observed the change of mitochondrial calcium in brain cell of NIDDM rats.And approached the effects of the spores of Ganoderma lucidum on the above mentioned indexes. METHODS The rat model of NIDDM was cstablished by using STZ. The effects of the spores of Ganoderma lucidum on mitochondrial calcium in brain cell of NIDDM rats were observed. RESULTS the NIDDM model was preparated successfully,In model group,the level of mitochondrial calcium were higher (P<0.05),commpared with the normal and ganoderma proup. CONCLUSION calcium ion participated damage in brain cell. The spores of Ganoderma lucidum can protecte brain of NIDDM rats. |
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| Keywords: | NIDDM brain cell mitochondrial calcium the spore of Ganoderma lucidum |
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