Interaction of biodegradable β-whitlockite ceramics with bone tissue: An in vivo study |
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| Authors: | Christel PAT Klein K de Groot AA Drissen HBM van der Lubbe |
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| Institution: | Department of Materials Science, School of Medicine and Dentistry, Free University, Amsterdam, The Netherlands |
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| Abstract: | The biodegradation of different porous β-whitlockite materials are studied by in vivo experiments, radiographie follow-ups and light microscopy observations. The materials were implanted in rabbit tibiae for 16 mnth. Micropores play an important role in the biodegradation rate. The resorbing materials evoke an inflammation with plasma cells. The resorption starts in the medulla, and the phagocytosed particles are removed to the lymph nodes. Normal bone function can be restored after all the implant material is resulted. |
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| Keywords: | Ceramics β-whitlockite implant material biodegradation |
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