| 血管生成与喉癌侵袭、转移的研究进展 |
| |
| 引用本文： | 王树楹,吕 梅,杜翠萍,吴丽华,姚艺文. 血管生成与喉癌侵袭、转移的研究进展[J]. 大连医科大学学报, 2011, 33(1): 86-89 |
| |
| 作者姓名： | 王树楹 吕 梅 杜翠萍 吴丽华 姚艺文 |
| |
| 作者单位： | 王树楹,WANG Shu-ying(大连市第六人民医院耳鼻咽喉科,辽宁,大连,116001);吕梅,杜翠萍,吴丽华,姚艺文,L(U) Mei,DU Cui-ping,WU Li-hua,YAO Yi-wen(大连医科大学,附属第一医院耳鼻咽喉科,辽宁,大连,116011) |
| |
| 摘 要： | 新生毛细血管的形成,对喉癌肿瘤细胞本身的增殖和生长是必不可少的,同时也是肿瘤侵袭、转移的必要条件.在肿瘤血管形成的机制中血管生成调节因子起着关键作用,这些因子能够控制血管生成发生、发展以及终止过程,并作为抗血管生成治疗的分子靶点受到关注.本文综述了比较重要的几种细胞活性因子:血管内皮生长因子(VEGF)、基质金属蛋白酶...
|
| 关 键 词： | 血管生成 喉癌 细胞因子 |
Research progress of angiogenesis in invasion and metastasis of laryngeal carcinoma |
| |
| WANG Shu-ying,L Mei,DU Cui-ping,WU Li-hua,YAO Yi-wen. Research progress of angiogenesis in invasion and metastasis of laryngeal carcinoma[J]. Journal of Dalian Medical University, 2011, 33(1): 86-89 |
| |
| Authors: | WANG Shu-ying L Mei DU Cui-ping WU Li-hua YAO Yi-wen |
| |
| Affiliation: | WANG Shu-ying,L(U) Mei,DU Cui-ping,WU Li-hua,YAO Yi-wen |
| |
| Abstract: | Angiogenesis is necessary for the cellular proliferation and growth of laryngeal carcinoma and is essential for tumor invasion and metastasis.Angiogenic regulatory factors play important roles in the mechanism of tumor neovascularization,controlling the development and termination of angiogenic progress.So they became the main targets for antiangiogenic therapies.We reviewed several representative cytokines regarding their clinical significance in laryngeal carcinoma,such as vascular endothelial growth factor(VEGF),matrix metalloproteinase(MMPs),integrin and angiogenin. |
| |
| Keywords: | angiogenesis laryngeal carcinoma cytokine |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《大连医科大学学报》浏览原始摘要信息 |
|
点击此处可从《大连医科大学学报》下载免费的PDF全文 |
|
