射频热凝术治疗原发性三叉神经痛的临床研究

目的评价射频热凝术治疗原发性三叉神经痛的近、中期临床疗效及安全性。方法将63例原发性三叉神经痛患者随机分成:治疗组(31例)及对照组(32例),治疗组采用数字减影脑血管造影(DSA)机引导下射频热凝术治疗,对照组采用常规药物治疗或封闭方法治疗,分别观察2组的临床疗效,并对治疗组中期疗效进行随访。结果治疗组总有效率96.8%,优良率61.3%,无严重不良反应发生,明显优于对照组总有效率65.6%、优良率28.1%,差异有统计学意义(χ2=9.91、7.01,P0.01),治疗组术后中期的临床疗效随访,总有效率仍为96.8%,2例复发,占6.5%,经第2次射频热凝术治疗完全止痛。结论 DSA机引导射频热凝治疗原发性三叉神经痛穿刺成功率高,近、中期临床疗效确切,安全性高。

Clinical study of radiofrequency thermocoagulation in the treatment of primary trigeminal neuralgia

Objective To evaluate the clinical efficacy and safety of DSA-guided radiofrequency themocoagulation on the treatment of primary trigeminal neuralgia in short-and mid-term prospect.Methods 63 cases of primary trigeminal neuralgia were randomly and divided into two groups,including the patients treated with radiofrequency themocoagulation(n=31),and those in control group(n=32) who treated with drugs or trigeminal nerve block.Clinical efficay was compared between the two groups,and the patients in treated with radiofrequency themocoagulation group were followed up for 24 hours to 6 months.Results The effective rate with radiofrequency themocoagulation was 96.8%,and the satisfactory rate was 61.3%,whereas it was 65.6% and 28.1% in the control group.The patients were followed-up survery 1 year after radiofrequency themocoagulation,and the effective rate was 96.8%,2 patients recurrenced andretreated with radiofrequeney thermocoagulation,the recurrence rate was 6.5%.Conclusion DSA-guided radiofrequeney thermocoagulation on the treatment of primary trigeminal neuralgia is effective and safe in short-and mid-term prospect.