不同供氧流量对新生儿头罩吸氧的吸入氧浓度和动脉血二氧化碳分压的影响

目的检测新生儿头罩吸氧时不同供氧流量下患儿血液中二氧化碳分压(PaCO2)与吸入氧浓度(FIO2)的变化关系,分析得出新生儿安全头罩用氧的规律。方法调节氧气流量,测定在不同流量下新生儿头罩内FIO2。结果氧气流量在3 L/min以下时,3组FIO2均小于35%,中小号头罩组有CO2潴留;氧流量在3～5 L/min时,中小号头罩组FIO2为35%左右,大号头罩组FIO2接近30%,小号头罩组有CO2潴留;氧流量在5～7 L/min时,中小头罩组FIO2为40%～50%,大号头罩组FIO2接近40%,3组均无CO2潴留;氧流量大于7 L/min时,3组FIO2均在50%以上,无CO2潴留。结论纯氧下,选择流量在3～5 L/min,选择大中号头罩吸氧相对安全。对于没有空氧混合仪及氧浓度检测设备的基层医院进行氧气治疗有一定指导作用。

Oxygen concentration analyzer combines with blood gas analysis to lead the choice of oxygen flow with oxygen hood for the newborn

Objective By monitoring the relationship of change between pressure of carbon dioxide(Paco2) and inspired oxygen concentration(Fio2) when the newborn oxygen hood with different flow of oxygen,to analyze and obtain laws of newborn’s safe oxygen hood.Methods The oxygen flow rate was adjusted,Fio2 and Paco2 in the hood under different oxygen flow were measured.Results When oxygen flow was under 3L/MIN,Fio2 of the all three groups was less than 35%,and medium and small hood groups had CO2 retention;when oxygen flow was between 3-5L/MIN,the Fio2 of medium and small hood groups was around 35% and Fio2 of large hood group was close to 30%,and small group hood had CO2 retention;when oxygen flow was between 5-7L/MIN,the Fio2 of medium and small hood groups was 40-50% while the large hood group was close to 40%,and three groups had no CO2 retention;when oxygen flow was greater than 7L/MIN,the Fio2 of three groups was above 50%,without CO2 retention.Conclusion When pure oxygen is used,the oxygen flow is between 3-5L/MIN,selection of the large and medium oxygen hood is relatively safe.It plays a guiding role for primary hospital without air-oxygen mixture equipment and oxygen concentration monitoring device.