氟哌利多与托烷司琼预防腹腔镜胆囊切除术后恶心呕吐的疗效观察

目的观察氟哌利多、托烷司琼预防腹腔镜胆囊切除术后恶心呕吐的临床疗效。方法选择60例择期行全凭静脉麻醉下腹腔镜胆囊切除术的患者,随机分为A、B、C组,每组20例,分别在开始缝合前静注0.9%氯化钠10ml(A组)、氟哌利多1.25mg(B组)、托烷司琼5mg(C组)。术毕清醒后拔管,观察记录术后24h患者发生恶心呕吐的情况。结果 B、C组的术后恶心呕吐发生率明显低于A组(P<0.05);B组与C组比较差异无统计学意义(P>0.05)。结论氟哌利多和托烷司琼均可显著降低腹腔镜胆囊切除术后恶心呕吐的发生率,二者疗效相当。

CLINICAL OBSERVATION OF PREVENTIVE EFFECTS OF DROPERIDOL AND TROPISETRON FOR NAUSEA AND VOMITING AFTER LAPAROSCOPIC CHOLECYSTECTOMY

Objective To compare the preventive effects of droperidol and tropisetron on nausea and vomiting after laparoscopic cholecystectomy.Methods 60 patients with general anesthesia underwent elective laparoscopic cholecystectomy were randomly divided into group A,group B and group C(n=20).Before suture,all patients in group A received 0.9% sodium chloride injection 10ml,group B droperidol 1.25mg,group C tropisetron 5 mg.Patients were extubated when they were conscious.The occurrence of nausea and vomiting 24 h after operation were observed and recorded.Results The occurrence rate of postoperative nausea and vomiting in group B and group C were significantly lower than that in group A(P<0.05).There was no significant difference between group B and group C(P>0.05).Conclusion Droperidol and tropisetron could significantly reduce the occurrence of nausea and vomiting after laparoscopic cholecystectomy.