米索前列醇用于足月妊娠引产的效果观察

目的观察米索前列醇对足月妊娠引产的效果及安全性。方法选择正常单胎、头位、足月妊娠且有引产指征而无禁忌证的184例初产妇，随机分为两组，观察组100例，用米索前列醇50μg阴道后穹隆置药引产；对照组84例，用催产素引产。结果观察组引产总有效率（92％）与对照组（78．6％）比较，差异具有显著性（P〈0．05），观察组临产发动时间及总产程均明显短于对照组（P〈0．05）。结论米索前列醇用于足月妊娠引产安全、有效，具有推广价值。

Effect of misoprostol in induction of labor in patients with term pregnancy

Objective To study the effect and safety of misoprostol in induction of labor in cases of term pregnancy. Methods One hundred and eighty- four primiparae with indication of induced labour in single fetus, head position, full -term pregnancy without contraindication were selected for this study. All these 184 women with normal term pregnancy were randomly divided into 2 groups： 100 cases in observed group were placed with 50μg misoprostol in posterior fornix of their vaginae, and 84 eases in control group were intravenously administrated with oxytocin.Resuits The successful rate of labor induction was 92% in observed group and 78.6% in control group . There was significant difference between these two groups （ P 〈 0.05 ）. The delivery course and total stage of labor in observed group were significantly lower than those of control group（ P 〈 0.05 ）. Conclusion The using of misoprostol for labor induction in women with term pregnancy is safe and effective, and it can be applied in clinics.