成人原位肝移植(附18例报告)

目的 研究原位肝移植治疗终末期肝病的临床效果。方法 在５年内为１８例终末期肝病病人实施原位肝移植手术，其中肝炎肝硬化１５例，肝癌３例。结果 手术死亡５例，病死率２７．２％，围手术期存活１３例（７７．８％）。术后并发症：腹腔出血４例，胆瘘２例。随访期间２例胆瘘病人死亡（分别于术后６个月和８个月），现存活１１例（６１．１％）生存时间均超过５个月，最长１例生存时间已５年半。结论 肝移植手术是最终末期肝病

Orthotopic liver transplantation in adults:a report of 18 cases

Objective To determine the efficacy of orthotopic liver transplantation (OLT) in treatment of end stage liver diseases. Methods From May 1994 to May 1999, 18 patients with the end stage liver diseases were treated with OLT in our department. Of the patients, 15 were with cirrhosis resulting from hepatitis B and 3 with hepatic cancer. Results Five patients died in the perioperative period (27.78%). Of the left 13 patients, 4 were reexplored because of bleeding in abdominal cavity on d 1 after operation and 2 presented with bile leak. The latter 2 died during the follow up. Other 11 patients have survived for 5 months to 5 years. Conclusions The liver transplantation is an effective means in treatment of end stage liver diseases. Reduction of complications and prevention of reinfection of hepatitis B virus after operation are critical for promoting successful rate of the operation to prolong survival time of the patients.