| 浅低温对犬全脑缺血再灌注后脑组织形态及脑功能的影响 |
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| 引用本文： | 王云姣,谭秀娟,蔡宏伟,麻兴利,徐启明. 浅低温对犬全脑缺血再灌注后脑组织形态及脑功能的影响[J]. 中南大学学报(医学版), 1996, 0(3) |
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| 作者姓名： | 王云姣 谭秀娟 蔡宏伟 麻兴利 徐启明 |
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| 作者单位： | Department of Anesthesiology，Xiangya Hospital，Hunan Medical University |
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| 摘 要： | 研究浅低温对犬心脏停跳复苏后脑组织形态学及脑功能的影响。缺血时间１８ｍｉｎ，再灌注８ｈ，观察神经机能及脑顶叶皮质形态学改变，并对顶叶皮层神经细胞及毛细血管进行体视学分析。结果表明，浅低温综合治疗可明显减轻神经细胞及毛细血管的损害，促进脑功能的恢复。
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| 关 键 词： | 低温，人工；再灌注损伤；脑；超微结构；疾病模型，动物；狗 |
EFFECTS OF MILD HYPOTHEKMIA ON NEURON MORPHOLOGY AND NEUROLOGIC FUNCTION IN DOGS FOLLOWING CARDIAC ARREST AND RESUSCITATION |
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| Wang Yunjiao, Tan Xiujuan ,Cai Hongwei, Ma Xinli. EFFECTS OF MILD HYPOTHEKMIA ON NEURON MORPHOLOGY AND NEUROLOGIC FUNCTION IN DOGS FOLLOWING CARDIAC ARREST AND RESUSCITATION[J]. Journal of Central South University. Medical sciences, 1996, 0(3) |
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| Authors: | Wang Yunjiao Tan Xiujuan Cai Hongwei Ma Xinli |
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| Abstract: | he authors investigated the effects of mild hypothermia on neuron morphology and neuro-logic function in dogs following cardiac arrest and resuscitation. The duration of complete globalbrain ischernia was 18 minutes and the reperfusion time was 8 hours. The function of nervoussystem and the morphology of cerebral cortex were observed.According to stereology,the au-thors measured the density=volume of neurons and capillaries in cortesx. The data indicate thatunder mild hypothermia neuron and capillary damage are decreased and the neurologic outcome isimproved after a 18 minutes cardiac arrest and resusciation in dogs. |
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| Keywords: | hypothermia induced reperfusion injury brain ultrastructure diseasemodel animal dogs |
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