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Angiolymphoid hyperplasia with eosinophilia (Kimura's disease). Apropos a case report with ultrastructural and histoenzymological study
Authors:G Chomette  S Boisnic  C Frances  M Auriol
Abstract:One case of angiolymphoid hyperplasia with eosinophilia is related in a 30-years old woman. This observations has all the characteristics of the disease: telangiectasic oedema, nodules and infiltrated areas located in the cervico-facial skin and also in the nasal and buccopharyngeal mucosa. Histologically, the proliferation is made of adult or young capillaries surrounded by inflammatory cells. The results of the peculiar morphological methods used here prove the endothelial nature of cells: high enzymatic activities of alkaline phosphatase and ATPases; factor VIII present on the cells; ultrastructural features characteristic of more or less differentiated vessels. Besides their nosologic interest, these methods may be useful for the diagnosis of this disease with the other vascular tumors.
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