局部点滴双氯灭痛或狄奥宁治疗人工晶体术后瞳孔膜的实验研究

目的 :通过用双氯灭痛或狄奥宁滴眼 ,观察对人工晶体植入术后瞳孔膜的防治作用。方法 :2 4只成年纯系新西兰白兔的 48只眼 ,随机分为 3组 :双氯灭痛治疗组 (A组 )、狄奥宁治疗组 (B组 )和空白对照组 (C组 )。 48只兔眼均行晶体囊外摘除及后房型人工晶体植入术 ;术后 1,3,5 ,7,14,2 1,30d定量动态观察人工晶体表现瞳孔膜的情况。结果 :A组的瞳孔膜低于B ,C组 (P <0 .0 5 ) ;B组瞳孔膜低于C组 (P <0 .0 5 )。结论 :双氯灭痛与狄奥宁滴眼均能有效治疗人工晶体植入术后瞳孔膜 ;双氯灭痛的疗效优于狄奥宁

Experimental study on using diclofenac sodium or dionine topically to treat fibrinous membrane after intraocular lens implantation

Objective To find a reasonable method for treating and preventing fibrinous membrane after intraocular lens (IOL) implantation by using diclofenac sodium or dionine topically. Methods Forty eight eyes of twenty four adult pure bred New Zealand rabbits were divided into three groups randomly. Group A: rabits received diclofenac sodium eyedrops; Group B: rabbits received dionine eyedrops; Group C: controlled. All the eyes received lens extraction combined with posterior chamber intraocular lens implantation. The fibrinous membrane was observed after 1,3,5,7,14,21 and 30 days postoperatively. Results The fibrinous membran in Group A was less than that of Group B and Group C, (P<0.05); the difference between group B and group C on fibrinous membrance was also statistically significant (P<0.05). Conclusion The study suggests that both diclofenac sodium and the dionine eyedrops can treat fibrinous membrane after IOL implantation. The effect of diclofenac sodium is better than that of dionine.