Severe Haemolytic Anaemia Complicating Infectious Mononucleosis

Summary: Severe haemolytic anaemia complicating infectious mononucleosis. R. K, Woodruff and A. J. McPherson, Aust. N.Z, J. Med., 1976, 6, pp. 569–570.
The case record of a patient suffering from infectious mononucleosis, complicated by severe haemolytic anaemia with overt intravascular haemolysis, is reported. Investigation of such cases usually shows a high titre of cold agglutinins with anti-i specificity. In the case reported, the results of serological investigations were atypical, and suggested that cold agglutinins with anti-l activity (rather than anti-i) were predominant in the aetiology of the haemolysis.