| 光照灭活病毒法对血浆成分的影响研究 |
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| 引用本文： | 李克勤,汪玲,郁正芹,相恒泉,袁海涛. 光照灭活病毒法对血浆成分的影响研究[J]. 放射免疫学杂志, 2007, 20(5): 474-475 |
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| 作者姓名： | 李克勤 汪玲 郁正芹 相恒泉 袁海涛 |
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| 作者单位： | 江苏省连云港市红十字中心血站,222001;江苏省连云港市红十字中心血站,222001;江苏省连云港市红十字中心血站,222001;江苏省连云港市红十字中心血站,222001;江苏省连云港市红十字中心血站,222001 |
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| 基金项目： | 本文部分项目检测由连云港市第二人民医院检验科协助完成,特此致谢 |
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| 摘 要： | 目的:观察了光照灭活病毒法对血浆中诸成分的免疫活性及生物指标的影响.方法:应用ZBK-YBM-01仪器于可见光下,在室温照射30min.结果:除凝血因子PT、KPTT有一定程度的延长外,其它血浆白蛋白、葡萄糖、无机盐、免疫球蛋白、补体C3、C4及血浆pH值均未受影响.血浆经蛋白电泳分析,电泳迁移率与未照射前组相同.结论:光照灭活病毒法对大多数血浆成分的影响不明显,具有重要的临床应用价值.
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| 关 键 词： | 病毒灭活 光照灭活 血浆成分 |
| 收稿时间： | 2007-07-12 |
| 修稿时间： | 2007-09-16 |
The Effect of Photo-Inactivation of Virus on Plasma Components |
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| Li Keqin, Wang Ling, Yu Zhengqin,et al.. The Effect of Photo-Inactivation of Virus on Plasma Components[J]. Journal of Radioimmanology, 2007, 20(5): 474-475 |
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| Authors: | Li Keqin Wang Ling Yu Zhengqin et al. |
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| Affiliation: | Lianyungang Center of Blood Station, Lianyungang, Jiangsu ,222001 |
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| Abstract: | Objective To investigate the effect of photo-inactivation of virus on immunological properties and biochemical ingredients of plasma.Methods Photo-inactivation was performed with ZBK-YBM-01 under visible light at room temprature for 30 min.Results Except that a few coagulation factors(PT and KPTT) were decreased,other parameters,immunoglobulins,C3,C4,including albumin,glucose,minerals as well as plasma pH were significantly not effected.No change of electrophoretic patterns was observed.Conclusion Photo-inactivation of virus could be safely done without significant effects on various plasma components and was definitely clinically applicable. |
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| Keywords: | virus inactivation photo - inactivation plasma components |
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