| 21例腺泡状软组织肉瘤的临床病理分析 |
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| 引用本文： | 周梅,赵刚,赵峰,李景英. 21例腺泡状软组织肉瘤的临床病理分析[J]. 临床与实验病理学杂志, 2010, 26(1) |
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| 作者姓名： | 周梅 赵刚 赵峰 李景英 |
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| 作者单位： | 1. 新疆医科大学附属肿瘤医院病理科,乌鲁木齐,830000
2. 新疆自治区中医院B超室,乌鲁木齐,830000 |
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| 摘 要： | 目的探讨腺泡状软组织肉瘤的临床病理学特征及其鉴别诊断。方法对21例ASPS的临床资料进行回顾性分析,对标本进行组织病理学观察及免疫组织化学研究。结果21例腺泡状软组织肉瘤,男性11例,女性10例,发病年龄4～56岁,平均25.9岁,发病部位主要位于下肢深部软组织内,镜下肿瘤细胞排列成腺泡状或实性,细胞巢之间可见窦状血管分隔,瘤细胞胞质内含丰富的嗜酸性颗粒。PAS染色,瘤细胞胞质内可见棒状结晶体,免疫组化:MyoD110例阳性,desmin4例阳性,S-1009例阳性,NSE11例阳性,Vim11例阳性,AE1/AE3、CK、EMA、SMA、MSA、Syn全部为阴性。结论ASPS是多见于青少年和青年的罕见肿瘤,但多数早期出现血液转移,切除后易复发,最终预后欠佳,结合临床病理学特征及免疫组化,可作出正确诊断。
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| 关 键 词： | 腺泡状软组织肉瘤 病理特征 |
Alveolar soft part sarcoma: a clinicopathological analysis of 21 cases |
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| ZHOU Mei,ZHAO Gang,ZHAO Feng,LI Jing-yin. Alveolar soft part sarcoma: a clinicopathological analysis of 21 cases[J]. Chinese Journal of Clinical and Experimental Pathology, 2010, 26(1) |
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| Authors: | ZHOU Mei ZHAO Gang ZHAO Feng LI Jing-yin |
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| Affiliation: | 1Department of Pathology/a>;Affiliated Tumor Hospital/a>;Xinjiang Medical University/a>;Wulumuqi 830000/a>;China/a>;2Department of Supersonic/a>;Chinese Medicine Hospital/a>;Xinjiang Uigous Autonomous Region/a>;China |
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| Abstract: | Purpose To investigate the clinical and pathological features and differential diagnosis of alveolar soft part sarcoma (ASPS).Methods The clinical data were retrospectively analyzed in 21 cases of ASPS.Histopathological and immunohistochemical changes of the tumors were also observed in the paraffin-embedded tissue samples.Results In 21 cases,11 were male and 10 females.Ages of the patients ranged from 4 to 56 years old,with mean 25.9 years old.The lesions were mainly located in the deep soft tissues of leg... |
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| Keywords: | alveolar soft part sarcoma pathological features |
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