显微手术治疗大脑半球中央回区脑胶质瘤的临床研究

目的探讨大脑半球中央回区脑胶质瘤患者显微神经外科手术治疗效果,为临床提供治疗策略。方法41例中央回区脑胶质瘤患者分成优势半球组和非优势半球组。用Kaplan-Meier法来评估术后患者的生存状况,KPS评分对比两组患者随访6个月及12个月的功能状况。结果两组患者在手术切除程度、手术后并发症、功能状况、生存状况等方面比较没有差别。结论优势半球中央回区脑胶质瘤术后生存状况与非优势半球中央回区脑胶质瘤术后相比无差异。因此,优势半球中央回区脑胶质瘤可以达到非优势半球脑胶质瘤同样的肿瘤切除程度。

A clinical research on the microneurosurgical treatment of gliomas located in gyri centrales of cerebral hemisphere

Objective To explore the therapeutic effect of gliomas in gyri centrales of cerebral hemisphere treated with microneurosurgical technique,and to provide clinical treatment strategies for such patients based on these data. Methods 41 patients with gliomas near gyri centrales were divided into the group of dominant hemisphere and the group of nondominant hemisphere. Kaplan-Meier method was used to assess the survival data and Kamofsky Performance Status(KPS) was used to compare the functional outcomes in 6 months and 12 months. Results The extent of tumor resection,postoperative complications,functional outcomes and the survival in two groups were no statistically significant. Conclusion There is no difference in survival between patients with gliomas in the gyri centrales of dominant hemisphere and those with gliomas in the gyri centrales of nondominant hemisphere. And the extent of gliomas resection in the gyri centrales of dominant hemisphere is the same as that of nondominant hemisphere.