| 342例羊水细胞染色体核型结果分析 |
| |
| 引用本文： | 黄飞飞,王兆才,廖世秀,王应太.342例羊水细胞染色体核型结果分析[J].实用诊断与治疗杂志,2003,17(4):254-255. |
| |
| 作者姓名： | 黄飞飞 王兆才 廖世秀 王应太 |
| |
| 作者单位： | 450003,郑州市,河南省人民医院遗传研究所 |
| |
| 摘 要： | 目的 :探索羊水细胞染色体核型分析的方法 ,减少染色体病患儿出生。方法 :对 3 42例具有产前诊断指征高风险孕妇抽取孕中期羊水细胞培养 ,制备中期细胞染色体 ,G显带分析。结果 :发现 2 3例染色体异常 ,占 6 7%,其中数目异常 4例 ( 17 3 9%) ,结构异常 16例 ( 69 5 7%) ,嵌合体 3例 ( 13 0 4%)。结论 :羊水细胞的染色体核型分析是染色体病产前诊断的确诊方法之一。
|
| 关 键 词： | 羊水细胞 异常染色体 核型 |
| 文章编号： | 1672-3457(2003)04-254-02 |
| 修稿时间： | 2003年1月6日 |
A karyotyping study on the chromosomes of ammiotic cells from 342 women |
| |
| HUANG Feifei,WANG Zhaocai,LIAO Shixiu,et al..A karyotyping study on the chromosomes of ammiotic cells from 342 women[J].Journal of Practical Diagnosis and Therapy,2003,17(4):254-255. |
| |
| Authors: | HUANG Feifei WANG Zhaocai LIAO Shixiu |
| |
| Institution: | HUANG Feifei,WANG Zhaocai,LIAO Shixiu,et al.Institute of Medical Genetics,Henan Provincial People's Hospital,Zhengzhou 450003,China [ |
| |
| Abstract: | Objective To explore the use of amniocentesis in prenatal analysis,and reduce the newborn with abnormal chromosome.Methods Amniocentesis was employed to detect amniotic cells collected from 342 pregnant women with high-risk prenatal diagnosis indications.Results It was shown by karyotype analysis that 23 cases(6.7%) were found with abnormal karyotype,in which 4 cases(17.89%) were found with abnormal numbers,16 cases(69.57%) were found with abnormal construction,and 3 case(3.04%) were somatic mosaicism.Conclusions It is indicated that amniocentesis and karyotyping is one of the most important methods for prenatal diagnosis. |
| |
| Keywords: | Amniotic cells abnormal chromosome karyotype |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
